Customization: | Available |
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Classification: | High Purity Material |
Content: | Standard |
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Phenibut Basic information |
Product Name: | Phenibut |
Synonyms: | 4-AMINO-3-PHENYLBUTANOIC ACID HYDROCHLORIDE;4-AMINO-3-PHENYLBUTIRIC ACID;-Amino-3-phenylbutyric acid hydrochloride;NA###4-Amino-3-phenylbutyric acid hydrochloride;PHENIBUTCAS NO.: 1078-21-3 Phenibut CAS NO.1078-21-3;Nootropics Powder Nutrition Supplement Phenibut for Fatigue Reduce CAS 1078-21-3;TIMTEC-BB SBB001567;PHENIBUT |
CAS: | 1078-21-3 |
MF: | C10H13NO2 |
MW: | 179.22 |
EINECS: | 214-079-6 |
Product Categories: | Amino Acid;Inhibitors;Organic acids;Nutritions & Sterides;API |
Mol File: | 1078-21-3.mol |
Phenibut Chemical Properties |
Melting point | 252.5°C (rough estimate) |
Boiling point | 311.75°C (rough estimate) |
density | 1.1248 (rough estimate) |
refractive index | 1.5710 (estimate) |
solubility | Free base: 35 mg/mL in DMSO (195.29 mM) at 25 °C (SellekChem, 2019).Hydrochloride salt (Cayman, 2016): 25 mg/ml in DMF; 20 mg/ml in DMSO; 14 mg/ml in ethanol; 10 mg/mL in PBS (pH 7.2). |
pka | 4.10±0.10(Predicted) |
form | solid |
color | White |
InChI | InChI=1S/C10H13NO2/c11-7-9(6-10(12)13)8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H,12,13) |
InChIKey | DAFOCGYVTAOKAJ-UHFFFAOYSA-N |
SMILES | C(O)(=O)CC(C1=CC=CC=C1)CN |
CAS DataBase Reference | 1078-21-3(CAS DataBase Reference) |
EPA Substance Registry System | Benzenepropanoic acid, .beta.-(aminomethyl)- (1078-21-3) |
Safety Information |
Hazard Codes | Xi |
HazardClass | IRRITANT |
HS Code | 2922498590 |
Toxicity | TDLo orl-hmn: 5 mg/kg:CNS BEXBAN 57,52,64 |
MSDS Information |
Phenibut Usage And Synthesis |
Description | Phenibut, also known as fenibut, phenigamma, and beta-phenyl-gamma-aminobutyric acid, is a derivative of the neurotransmitter GABA. It was developed in Russia,and there it has been used clinically since the 1960s to treat anxiety and related conditions,including insomnia(Lapin,2001). Phenibut has anxiolytic properties and is commonlycompared to and baclofen.Structurally,phenibut issimilar to GABA, with the addition of the phenyl ring. This allows thecompound to more easily cross the blood-brain barrier, but also changesits activity profile (Shulgina,1986). Scientific studies demonstrate that phenibut can be safely used to treat anxiety, depression,epilepsy, speech disorders, and insomnia. |
Uses | 4-amino-3-phenylbutanoic acid (cas# 1078-21-3) is a GABAA receptor agonist, used for treatment of disorders influenced by dysfunction of pancreatic β cells and also used in combination with other agents. |
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