Classification: | High Purity Material |
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Specific Usage: | Pratical Use |
Content: | Standard |
Usage: | Laboratory Reagents |
Source: | Extract Natural Things |
Habit Appellation: | Chemical Medicine |
Samples: |
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Customization: |
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Product Name: | Progesterone |
Synonyms: | PROGESTERONE-WATER SOLUBLE;progestin;PROGESTERONE;PRIMOLUT;Glanducorpin;Gynlutin;gynoluton;Gynolutone |
CAS: | 57-83-0 |
MF: | C21H30O2 |
MW: | 314.46 |
EINECS: | 200-350-6 |
Product Categories: | Plant extract;Pharma material;Intracellular receptor;Steroid and Hormone;API;ENDOMETRIN;FINISHED MEDICINE;Steroids;ketone;Biochemistry;Steroids (Others);Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitors;MI;57-83-0 |
Mol File: | 57-83-0.mol |
Progesterone Chemical Properties |
Melting point | 128-132 °C (lit.) |
alpha | 186 º (c=1, ethanol) |
Boiling point | 394.13°C (rough estimate) |
density | d23 1.166; d20 1.171 |
refractive index | 182 ° (C=2) |
Fp | 2ºC |
storage temp. | room temp |
solubility | H2O: 25 mg/mL, may be clear to slightly hazy |
form | powder |
color | Yellow to yellow-brown |
Water Solubility | <0.1 g/100 mL at 19 ºC |
Merck | 7773 |
BRN | 1915950 |
BCS Class | 4 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
InChIKey | RJKFOVLPORLFTN-LEKSSAKUSA-N |
LogP | 3.870 |
CAS DataBase Reference | 57-83-0(CAS DataBase Reference) |
NIST Chemistry Reference | Progesterone(57-83-0) |
EPA Substance Registry System | Progesterone (57-83-0) |
Uses | The main physiological effects of progesterone: 1. Progesterone can maintain the female animal pregnancy, and cause a series of physiological changes, such as inhibition of female estrus. 2. Progesterone has the power to promote the thickening of the lining of the uterus, promote the bending of the gland and to increase secretion function. 3. Progesterone can inhibit the peristalsis of the uterus, and contribute to the cervix contraction, secretion of mucus, etc.. These physiological changes provide suitable environment for the operation, growth and development of early embryos, as well as the continued growth of the fetus. 4. Small amount of progesterone is also used in combination with the hormone estrogen to promote female estrus. The synergy between progesterone and prolactin can promote the development of mammary glands. 5. Progesterone is involved in the feedback regulation of the hypothalamus and anterior pituitary, which makes the balance of the animal reproductive hormones. In vivo, progesterone content of all sorts of livestock follicular phase is below 1 ng/ml, while in bovine corpus luteum period is approximately 4 ng/ml, pregnancy period is about 18 ng/ml. 6. Formerly biochemical study shows that progesterone modulates action as progestogens, clinical for the treatment of habitual abortion, dysmenorrhea, amenorrhea and other symptoms. One of progesterone's most important functions is as hormone drugs, to promote and maintain the uterine changes in the early stage of pregnancy, used in habitual abortion, irregular menstruation, etc.. In addition, progesterone also behaves as steroid hormone drug as well as progestogens, which is used in treatment of threatened abortion. |
Uses | Progesterone is used as a contraceptive, for amenorrhea, for premenopausal syndrome, infertility, incomplete pregnancies, and anovulatory uterine bleeding. |
Uses | Steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.This compound is a contaminant of emerging concern (CECs). |
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